Zydus Lifesciences Ltd

Sigrima 420mg Injection

420mg/14ml

Sigrima 420mg Injection is a targeted therapy manufactured by Zydus Lifesciences, containing pertuzumab, a recombinant humanized monoclonal antibody. It is used in the treatment of …

Oncology & Cancer Care

Sigrima 420mg Injection - 420mg/14ml

Complete information about this pharmaceutical product including specifications, manufacturer details, and availability.

Sigrima 420mg Injection
Sigrima 420mg Injection
Sigrima 420mg Injection

Sigrima 420mg Injection

By Zydus Lifesciences Ltd

₹ 63,510/Vial ₹ 74,995/Vial
Save 15% off MRP

All prices are inclusive of taxes

Dosage

420mg/14ml

Pack Size

1 Vial of 14ml

Active Ingredient/Salt

Pertuzumab

Available Schemes

Sigrima 420mg + Sigrima 420mg Free as loading dose.
Additional Free Sigrima 420mg dose after 17th cycle.
Plus: Trastuzumab, Docetaxel, Paclitaxel, and Peg-Grafeel are also provided free as per prescription requirement.

Product Description

Sigrima 420mg Injection is a targeted therapy manufactured by Zydus Lifesciences, containing pertuzumab, a recombinant humanized monoclonal antibody. It is used in the treatment of HER2-positive breast cancer. Pertuzumab works by binding to the HER2 receptor on cancer cells, preventing the receptor from pairing with other HER family receptors and thereby blocking cell growth and survival signals. Sigrima is typically used in combination with trastuzumab and chemotherapy in both early and metastatic stages of HER2-positive breast cancer. The medicine is administered intravenously under medical supervision. Macarius Health provides genuine oncology medications like Sigrima at affordable rates with secure and prompt nationwide delivery.

Key Benefits

* Specifically targets HER2-positive breast cancer cells
* Prevents HER2 dimerization and downstream signaling
* Often used in combination with trastuzumab and taxanes
* Improves response rates and disease-free survival
* Backed by extensive clinical experience in Indian oncology practice

Price

₹ 63,510/Vial

₹ 74,995/Vial

Save 15% off MRP

Dosage

420mg/14ml

Pack Size

1 Vial of 14ml

Manufacturer

Zydus Lifesciences Ltd

Active Ingredient

Pertuzumab

Frequently Asked Questions

What is Sigrima 420 mg Injection for?

Sigrima 420 mg Injection contains pertuzumab and is used to treat certain types of HER2‑positive breast cancer, including cases where the cancer has spread or is advanced. Your doctor will explain why it has been prescribed for you and how often you will receive it.

How do I take Sigrima 420 mg Injection?

This injection is given by a trained healthcare professional via an intravenous (IV) infusion in a clinic or hospital. You will not administer it yourself. Your doctor will decide the dose schedule based on your treatment plan.

What side effects should I watch for?

Common side effects may include nausea, vomiting, hair loss, fatigue (tiredness), diarrhea, rash, and low blood cell counts. Less common but serious side effects may include heart problems, lung issues, severe infusion reactions (such as fever, chills, or trouble breathing), and increased risk of infection. Contact your doctor immediately if you notice chest pain, shortness of breath, sudden swelling of legs or arms, yellowing of skin or eyes, or heavy bleeding.

Where can I get Sigrima 420 mg Injection?

You can get Sigrima 420 mg Injection from Macarius Health. Contact our team via the website or WhatsApp to check availability and pricing. We provide authentic injections with delivery across Delhi, NCR and other parts of India.

How should I store Sigrima 420 mg Injection?

Store Sigrima 420 mg Injection in the refrigerator at 2 °C to 8 °C and protect it from light. Keep it in its original packaging and out of reach of children.

Can I take Sigrima 420 mg Injection with other medicines?

Yes, but you should tell your doctor about all other medicines, supplements or herbal products you are taking. Sigrima may interact with treatments that affect your heart, lungs, liver, or immune system.

Is it safe during pregnancy or breastfeeding?

Sigrima 420 mg Injection is generally not recommended during pregnancy or while breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, please consult your oncologist before using it.

How long does it take to get Sigrima 420 mg Injection delivered?

Macarius Health arranges safe and prompt delivery of Sigrima 420 mg Injection. In Delhi and NCR, priority delivery is often available when in stock. For other cities across India, delivery typically takes 1–4 business days. Bulk orders for hospitals and clinics are handled on request.

Why Choose Sigrima 420mg Injection?

We ensure the highest quality standards and authentic pharmaceutical products for your healthcare needs.

Authentic Product

100% authentic Sigrima 420mg Injection sourced directly from Zydus Lifesciences Ltd.

Quality Control

Rigorous quality checks and WHO-GMP certified storage facilities ensure product integrity.

Fast Delivery

Quick and secure delivery with proper cold chain management for temperature-sensitive products.

Expert Support

Our pharmaceutical experts provide technical support and guidance for all your medication needs.

Alternative Medicines with Same Salt

Discover other products containing the same active ingredient (Pertuzumab) that may serve as alternatives.

Perjeta 420mg Injection - Alternative Medicine
Substitute
Same Salt
Roche Products India Pvt Ltd

Perjeta 420mg Injection - 420mg

Category: Oncology & Cancer Care

₹ 2,28,490/Vial ₹ 2,58,339/Vial
View Details
Womab 420mg Injection - Alternative Medicine
Substitute
Same Salt
Dr. Reddy's Laboratories Ltd

Womab 420mg Injection - 420mg/14ml

Category: Oncology & Cancer Care

₹ 57,500/Vial ₹ 74,992/Vial
View Details

Showing 2 of available alternatives

Important: These are alternative medicines with the same active ingredient. Please consult with your healthcare provider before making any substitutions.

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